5-Phenyl-1,3-oxazole-4-carboxylic acid

5-Phenyl-1,3-oxazole-4-carboxylic acid - Names and Identifiers

Name	5-Phenyloxazole-4-carboxylic acid
Synonyms	4-Carboxy-5-phenyl-1,3-oxazole 5-Phenyloxazole-4-carboxylic acid 5-phenyl-4-oxazolecarboxylic acid 5-PHENYL-OXAZOLE-4-CARBOXYLIC ACID 4-Oxazolecarboxylic acid, 5-phenyl- 5-PHENYL-1,3-OXAZOLE-4-CARBOXYLIC ACID 5-Phenyl-1,3-oxazole-4-carboxylic acid
CAS	99924-18-2
InChI	InChI=1/C10H7NO3/c12-10(13)8-9(14-6-11-8)7-4-2-1-3-5-7/h1-6H,(H,12,13)

5-Phenyl-1,3-oxazole-4-carboxylic acid - Physico-chemical Properties

Molecular Formula	C10H7NO3
Molar Mass	189.17
Density	1.32g/cm³
Melting Point	181 °C
Boling Point	354.73°C at 760 mmHg
Flash Point	168.335°C
Vapor Presure	0mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.587

5-Phenyl-1,3-oxazole-4-carboxylic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37/39 - Wear suitable gloves and eye/face protection
HS Code	29349990
Hazard Note	Irritant

5-Phenyl-1,3-oxazole-4-carboxylic acid - Introduction

Pentaphenyl 1,3 oxazole-4-carboxylic acid (pentaphenyl) is an organic compound with the molecular formula C11H7NO3 and a relative molecular mass of 205.18. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline solid
-Melting point: 166-169 ° C
-Stability: relatively stable under normal temperature and pressure, but may decompose under high temperature, strong acid or strong alkali conditions

Use:
-Pentaphenyl 1,3 oxazole-4-carboxylic acid is an important organic synthesis intermediate, commonly used in organic synthesis reactions.
-It can be used as a key raw material in drug development and manufacturing in the biomedical field.

Method:
Pentaphenyl 1,3 oxazole-4-carboxylic acid can be synthesized by the following steps:
1. First, Aniline reacts with acetic anhydride to produce aniline acetic anhydride.
2. Then, aniline acetic anhydride is reacted with Cyanogen cyanide to obtain 5-phenyl -1, 3-oxazole-4-carboxamide.
3. Finally, 5-phenyl -1, 3-oxazole-4-carboxamide is subjected to an acid hydrolysis reaction to obtain the final product pentaphenyl 1,3 oxazole-4-carboxylic acid.

Safety Information:
-Pentaphenyl 1,3 oxazole-4-carboxylic acid is generally considered to be relatively safe under normal use conditions, but it is still necessary to pay attention to follow laboratory operating procedures and safe operating methods.
-This compound may be irritating to the eyes, skin and respiratory tract, so avoid touching the skin and eyes during contact, and ensure that the laboratory is well ventilated.
-Wear appropriate protective equipment such as goggles, lab gloves, and face shields when handling the compound.
-If the compound is accidentally inhaled or ingested, seek medical attention immediately.

Last Update：2024-04-09 21:01:54